Molecular Cell Biology

Prof. Dr. Klemens Rottner


TU Braunschweig
Zoological Institute
Molecular Cell Biology
Biocenter
Spielmannstr. 7
38106 Braunschweig
Germany
Tel.: +49 (0)531 391 3256






Research Interests

    Assembly, disassembly and interplay between distinct cellular actin structures

  • Regulation of the actin cytoskeleton by Rho-family GTPases

  • Exploitation of the actin cytoskeleton by microbial pathogens

  • Force development and mechanics in cell protrusion and migration

  • Actin dynamics in neuronal development and plasticity


Technology and Methods
  • Advanced live-cell imaging techniques using widefield, confocal or TIRF optics

  • Dissection of actin turnover using photomanipulation and microinjection techniques

  • Functional interference with key regulators of cellular actin assembly employing gene inactivation, RNAi and/or genome editing

  • Dissection of actin cytoskeleton functions in bacterial infections